首頁 > 網路資源 > 大同大學數位論文系統

Title page for etd-0105109-150800


URN etd-0105109-150800 Statistics This thesis had been viewed 3164 times. Download 4619 times.
Author Yao-Chung Chang
Author's Email Address realuminumin@hotmail.com
Department Bioengineering
Year 2008 Semester 1
Degree Master Type of Document Master's Thesis
Language zh-TW.Big5 Chinese Page Count 80
Title Extraction of glucosamine derivatives and the applications on the
modification of biomedical materials
Keyword
  • modification
  • chitosan
  • chitosan
  • modification
  • Abstract This thesis developed the extraction methods for extracting glucosamine from
    animal by products. Hyaluronic acid was extracted from the comb of roosters. The goal is
    to enhance production rate as well as the purity of hyaluronic acid. The production rate of
    hyaluronic acid was 0.50% for the first extraction, 0.63% for the second extraction, and
    0.13% for the third extraction. HPLC was used to determine the purity of the hyaluronic
    acid. Chitin and chitosan from shrimp shell was another source of glucosamine. The
    production yield was 6.91% when extracted with alkaline solution. Chondroitin from pig
    ears and pig trachea was obtained with acetic acid extraction process. The production
    yield from pig ears is 7.15% while the production yield from pig trachea is .07%.
    The glucosamines obtained from animal were used in modification experiments. We
    used the Plasma treatment method to graft glucosamine onto different materials, including
    pHBV membrane and sutures. The cell proliferation and adherence of pHBV
    (poly(3-hydroxybutyrate-co-3-hydroxyvalerate))membrane also can be further
    improved by plasma treatment. Biodegradable sutures, Polyglactin, grafted with chitosan
    were tested to determine it’s properties. The results indicate that modified sutures has
    better antiseptic property than unmodified sutures.
    Advisor Committee
  • Chung-Yih Wang - advisor
  • Files indicate in-campus access immediately and off-campus access at one year
    Date of Defense 2008-12-05 Date of Submission 2009-01-05


    Browse | Search All Available ETDs