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Title page for etd-0210114-145712


URN etd-0210114-145712 Statistics This thesis had been viewed 1372 times. Download 0 times.
Author Jie-Yi Jiang
Author's Email Address wawachiang17@gmail.com
Department Bioengineering
Year 2013 Semester 1
Degree Master Type of Document Master's Thesis
Language zh-TW.Big5 Chinese Page Count 80
Title RESPIMATR INHALER DELIVERY SYSTEM FOR INHALATION THERAPY IN MECHANICALLY VENTILATED,IN VITRO
Keyword
  • Chronic obstructive lung disease
  • drug delivery
  • Tiotropium
  • Respimat inhaler
  • Respimat inhaler
  • Tiotropium
  • drug delivery
  • Chronic obstructive lung disease
  • Abstract Respimat R inhaler equipped with Tiotropium bromide, which is a long-acting anticholinergic agent. According to 2013 Global Initiative for Chronic Obstructive Pulmonary Disease Organization(GOLD) treatment standards, long-term anticholinergic tiotropium can selectively inhibit M3 and M1 receptors. The duration of action of Tiotropium is more than 24 hours,which can reduce the probability of COPD exacerbations and hospitalizations, improve symptoms and health status, and increase the effectiveness of pulmonary rehabilitation.
     If Respimat R inhaler can properly connect to a mechanical ventilator to deliver drugs for patients with respiratory failure, it will improve the quality of care. This study designed a method to connect the inhaler to ventilator to improve the deliver of drug into lung. The delivery amount of drug was analyzed with High Performance Liquid Chromatography.
    Advisor Committee
  • Chung-Yih Wang - advisor
  • Dey-Chyi Sheu - co-chair
  • Ming-Chou Chiang - co-chair
  • Files indicate not accessible
    Date of Defense 2014-01-06 Date of Submission 2014-02-11


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