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The defense date of the thesis is 2014-02-11
The current date is 2019-06-20
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URN etd-0210114-145751 Statistics This thesis had been viewed 905 times. Download 0 times. Author Shiou-Mei Chang Author's Email Address No Public. Department Bioengineering Year 2013 Semester 1 Degree Master Type of Document Master's Thesis Language zh-TW.Big5 Chinese Page Count 53 Title DURING THE DIFFERENT DIAMETER ENDOTRACHEAL TUBE METERED AEROSOL DELIVERY EFFECT Keyword Positive pressure mechanical ventilation Chronic lung disease of infancy Chronic lung disease of infancy Positive pressure mechanical ventilation Abstract Chronic lung disease of infancy refers to all infants in the neonatal period suffered lung damage caused by the final abnormal lung changes. Due to the high lung airway resistance, the disease is often associated with recurrent wheezing, giveg short-acting inhaled Beta2-adrenergic agonist can relieve bronchial contracture and improve ventilation. Inhaled steroids is also used as anti-inflammatory drugs to reduce bronchodilator usage, improve ventilation, reduce the oxygen concentration and shorten ventilator for several days.
The purpose of this study is to simulate the positive pressure mechanical ventilation through an endotracheal tube which connected with different device directly to assist the delivery of inhaled drugs,corticosteroid-Duasma. High Performance Liquid Chromatography was used to analzye the deposition amount of drug. The influence of inner diameter endotracheal on the delivery efficiency tube was studied. The results suggest that the bigger endotracheal tube increase the drug delivery efficiency.
Advisor Committee Chung-Yih Wang - advisor
Dey-Chyi Sheu - co-chair
Ming-Chou Chiang - co-chair
Files Date of Defense 2014-01-06 Date of Submission 2014-02-11