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The defense date of the thesis is 2014-07-10
The current date is 2019-04-25
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URN etd-0708114-154855 Statistics This thesis had been viewed 846 times. Download 1 times. Author Yin-Pei Chang Author's Email Address No Public. Department Chemical Engineering Year 2013 Semester 2 Degree Master Type of Document Master's Thesis Language zh-TW.Big5 Chinese Page Count 80 Title Transient Temperature Distribution and Expansion of Thermal Lesion Region around a Cylindrical Heat Source in an in vitro Tissue Keyword Thermal Lesion Region Temperature Distribution Temperature Distribution Thermal Lesion Region Abstract Transient temperature distribution and expansion of thermal lesion
region around a cylindrical heat source in an in vitro tissue has been
studied. The search works include: 1. Solving the temperature profiles near the heating source as function of time by use of the mathematical model developed earlier ; 2. Conducting experiments in an in vitro tissue (pork liver) and performing nonlinear data regression to obtain the parameters in the model; 3. Comparison between model calculations and experimental data; 4. Using temperature profiles to calculate thermal lesion region as function of time.
The results show that model calculations agree well with experimental data, with an average error of 2.264℃. The closer the position to the center of the heating source, the higher the temperature. The temperature drops fast along the radial axis, due that the heating source is at the center of the tissue and the heat conductivity of the tissue is small.
From the contours of average error (Erms), it can be found that the effect of parameters on Erms is small near the optimal position. In other words, small perturbation in parameter estimation does not affect the accuracy of the mathematical model.
The simulation results have been used to plot T(r,z) at various times to show the variation of temperature profiles statically. Computer animation has also been generated to show the variation of temperature profiles dynamically. Similarly, the variation of thermal legion region has been shown statically and dynamically. This computer simulation and animation can be used as reference for doctors who treat tumor by thermal therapy.
Advisor Committee Jan-Chen Hong - advisor
none - co-chair
none - co-chair
Files Date of Defense 2014-07-01 Date of Submission 2014-07-10