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URN etd-0814106-111418 Statistics This thesis had been viewed 2761 times. Download 1071 times. Author Szu-Jung Chiu Author's Email Address firstname.lastname@example.org Department Materials Engineering Year 2005 Semester 2 Degree Master Type of Document Master's Thesis Language English Page Count 97 Title Cold Plasma Deposited Organic Film on Stainless Steel to Improve Corrosion Resistant and Cell Attachment Keyword cell attachment plasma modification photo-induced graft corrosion resistant corrosion resistant photo-induced graft plasma modification cell attachment Abstract Stainless steels were widely used in biomaterials due to their high impact strength, high resistance to wear, ductile, absorption of high strain energy properties. However, the disadvantages of stainless steels were low biocompatibility and will corrosion in physiological environment. Besides, stainless steels are an inorganic and inert materials, will limited its surface drug immobilization and medical application. Chondroitin-6-sulfate (C-6-S) is the bulk of the matrix that builds vertebral discs, ligaments, cartilage and other connective tissues. It was widely distribution in human body, so it’s a biocompatible biomolecular. The easy way of improve biocompatibility of specimens is to immobilize biomolecular on the surface. In this study, the plasma deposition methods were used to obtain insulator and anticorrosion coating, and subsequent to surface graft polymerization of water soluble monomers for immobilized chondroitin-6-sulfhate to improve cell attachment. From FTIR and ESCA, the C-6-S were successful immobilized on specimens. The potential dynamic tests results shown that stainless steel through plasma deposited Hexamethyldisilazane (HMDSZ), the corrosion behavior can be controlled. Future more, the hydrophilic and biocompatibility can be improve after graft polymerization of water soluble monomers acrylic acid and then immobilized chondroitin-6-sulfhate through EDC (carbodiimide) cross linked. Advisor Committee Ko-Shao Chen - advisor
J. D. Liao - co-chair
Tai-I Wu - co-chair
Files Date of Defense 2006-06-19 Date of Submission 2006-08-14