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Title page for etd-0825109-115423


URN etd-0825109-115423 Statistics This thesis had been viewed 1761 times. Download 20 times.
Author Chia-chen Cheng
Author's Email Address No Public.
Department Bioengineering
Year 2008 Semester 2
Degree Master Type of Document Master's Thesis
Language zh-TW.Big5 Chinese Page Count 96
Title The function of sake lees after fermented by lactic acid bacteria
Keyword
  • Sake-lees
  • Anti-cancer proliferation
  • Whiting
  • Functionality
  • Functionality
  • Whiting
  • Anti-cancer proliferation
  • Sake-lees
  • Abstract There are many report have exhibit about Lactic acid bacteria, which can improve intestine discomfortable and Infectious diarrhea, and also improving immunization system. In cancer prevent, it’s already prove that can decrease some types of cancer. In this study, the five lactobacillus strains isolated from local Taiwanese fermented vegetables were used to fermented with different concentrations of sake lees extract (use different solvent extract, 10, 1, 0.1 mg/ml), and the supernatant filtrates were used to keep skin whitening and inhibition cancer cell growth. According to the results, to inhibit Hepatocellular Carcinoma and colon cells growth, cell survivability well decrease when enhancing concentrations of sake lees extract, and the supernatant filtrates from Lb. plantanum E38 could obviously inhibit the mushroom tyrosinase activity of 54 % , and decrease melanin contents of B16-F0 cell line of 54 % , equal to 3.4 μg/ml melanin. DPPH radical scavenging effect well decrease to reduce concentrations of sake lees extract for the most part. The tyrosinase inhibitory compounds contained in supernatant filtrates identify as linoleic acid using HPLC. The cancer inhibitor maybe inoleic acid isomers, presently have many report about inoleic acid isomers can anti-inflammatory and anticarcinogenic properties. Therefore, the fermentation products from sake lees by the lactobacilli will be very useful for application in the cosmetic and anticarcinogenic medicine.
    Advisor Committee
  • Tsong-rong Yan - advisor
  • Ming-tse Lin - co-chair
  • Roch-chui Yu - co-chair
  • Files indicate in-campus access only
    Date of Defense 2009-07-27 Date of Submission 2009-08-26


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