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Title page for etd-0909116-133533


URN etd-0909116-133533 Statistics This thesis had been viewed 761 times. Download 0 times.
Author Yu-wen Su
Author's Email Address No Public.
Department Bioengineering
Year 2015 Semester 2
Degree Master Type of Document Master's Thesis
Language zh-TW.Big5 Chinese Page Count 112
Title The Process Design for Producing Berberine by Different Bio-materials and its Economic Analysis
Keyword
  • Coptis chinensis
  • Economic benefits
  • Phellodendron amurense
  • Berberine hydrochloride
  • Radix berberidis
  • Berberine
  • Berberine
  • Radix berberidis
  • Berberine hydrochloride
  • Phellodendron amurense
  • Economic benefits
  • Coptis chinensis
  • Abstract ABSTRACT
      Berberine, a common alkaloid of isoquinoline alkaloids, can be obtained not only through extraction from Coptis chinensis, Phellodendron amurense, and Radix Berberidis, but also from chemical synthesis. Berberine was used in treatments for diarrhea and enteritis, but recently pharmacological studies confirmed that Berberine has obvious effect of lowering insulin-resistance, cholesterol, and heart failure, and also proved that Berberine is an excellent agent for anti-arrhythmic, anti-inflammatory, anti-platelet, and anti-proliferation of vascular smooth muscle cells. This study compared the six kinds of process methods producing Berberine, and also simulated the commercial production process to identify the most economically beneficial production model. The simulation results shown the best case was the extraction method from Coptis chinensis of 5,532 kg/year. The production cost of berberine was estimated as 571 NT $/kg. The annuals gross-profit was 6,245,000 NT$. Although the highest Berberine content was from Coptis chinensis, which is slow growth and less sources, therefore most of the commercial production of Berberine was the extraction from Radix Berberidis.
    Key words: Berberine, Berberine hydrochloride, Radix berberidis, Phellodendron amurense, Coptis chinensis, Economic benefits.
    Advisor Committee
  • Prof. C. Will Chen - advisor
  • Files indicate in-campus access immediately and off-campus access at 5 years
    Date of Defense 2016-07-25 Date of Submission 2016-09-12


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