||In this thesis, 3-(3-(dimethylamino)propylamino)-2-hydroxypropyl methacrylate (G-D) was synthesized by glycidyl methacrylate (GMA) and 3-Dimethylaminopropyl amine (DMPA) at first. Next G-D was used to prepared hydrogel with acrylamide (AmGx series), N-isopropyl acrylamide (NGx series) and sodium acrylate (SAGx series), where x represents the molar ratio of G-D. The effects of G-D on the hydrogel properties such as activation energy of gelation, swelling ratio, the impact of specific conditions, mechanical properties and drug releasing was investigated. G-D was expected to replace the accelerator: TEMED in the thermal polymerization in this study, and the results showed that the activation energy of gelation decreased with an increase of the G-D content for all hydrogels, and the results also indicated that acrylamide had the lowest activation energy of gelation and N-isopropyl acrylamide had the highest activation energy. The swelling ratios of hydrogels increased with an increase of the G-D content for acrylamide and N-isopropyl acrylamide hydrogels, but the sodium acrylate hydrogel showed the opposite. In terms of stimulus-response behavior, the swelling ratio of acrylamide hydrogel was decreased significantly at acetone content of 40 wt%. The critical gel transition temperature (CGTT) is at 32 ℃ for N-isopropyl acrylamide hydrogel, but the CGTT was increased with the increasing content of G-D. The highest CGTT was uptake to 44 ℃. For the pH-responsive of sodium acrylate hydrogels, the swelling ratio of sodium acrylate hydrogel increased with an increase of pH, but decreased with an increase of the G-D content. For the mechanical properties, crosslinking densities (ρX) were all increased when G-D was introduced into acrylamide and N-isopropyl acrylamide hydrogel, but AmG5 and NG5 hydrogel had the maximum mechanical strength. For drug-releasing, NG10 hydrogel had the highest drug-absorption which could reach 535 ppm caffeine /g. And the NG7.5 hydrogel had the highest releasing rate of 98.1%.