首頁 > 網路資源 > 大同大學數位論文系統

Title page for etd-0927104-173532


URN etd-0927104-173532 Statistics This thesis had been viewed 3427 times. Download 31 times.
Author Wei-Cheng Chen
Author's Email Address No Public.
Department Bioengineering
Year 2003 Semester 2
Degree Master Type of Document Master's Thesis
Language zh-TW.Big5 Chinese Page Count 103
Title Preliminary screening of Chinese herbal medicine with tyrosinase inhibitory activity
and antioxidant properties
Keyword
  • tyrosinase inhibitory
  • Chinese herbal medicine
  • antioxidant activity
  • antioxidant activity
  • Chinese herbal medicine
  • tyrosinase inhibitory
  • Abstract Abstract
    With the increasing demand of natural whitening and antioxidant ingredient, preliminary screening of hot water extracts from sixty Chinese herbal medicines with tyrosinase inhibitory activity and antioxidant properties was conducted in this study. The results showed that 14 out of 60 Chinese herbal medicines, including Rhus chinensis, Paeonia suffruticosa, Ginkgo biloba, Ligustium Wallichii, Polygala tenuifolia , Cinnamomum cassia , Acanthopanax gracilistylus , Nelumbo nucifera, Baphicacanthes cusia, Carthamus tinctorius, Rheum tanguticum , Rose taiwanensis , Scutellaria baicalensis and Pueraria Pseuo-hirsut , exhibited more than 70% of tyrosinase inhibitory activity. On the other hand, no inhibitory tyrosinase activity was found in Eriobotrya japonica.
    Among fourteen Chinese herbal medicines with higher inhibition activity of tyrosinase, R. chinensis, R. laevigata, R. tanguticum, N. nucifera, B. cusia and A. gracilistylus showed higher DPPH radical scavenging activity.The IC50 of DPPH radical scavenging activity ranged from 0.15 to 0.66 mg/ml. The higher antioxidant activity determined by conjugated diene method was shown by R. chinensis, followed by A.gracilistylus, R. laevigata, R. tanguticum, B. cusia and N. nucifera was meanwhile,the strongest reducing power was also shown by R. chinensis, followed by R. laevigata, R. tanguticum, N.nucifera, A. gracilistylus and B.cusia. The reducing power of R. chinensis, was 1.6 times that of BHA and 2.3 times that of Vitamin C. Reducing power increased with increasing concentration of hot water extract of R. laevigata, R. tanguticum, A.gracilistylus and B. cusia. The higher amounts of total phenolics were noted in R. chinensis, R. laevigata, R. tanguticum, N. nucifera, A. gracilistylus and B. cusia. Among fourteen tested Chinese herbal medicines, 846,586,375,220,124 and 102 mg of gallic acid equivalent per gm dry weight of hot water extract were obtained in R. chinensis, R. laevigata, R. tanguticum, N. nucifera, A. gracilistylus and B. cusia, respectively, In conclusion, six Chinese herbal medicines with higher tyrosinase inhibitory activity and antioxidant properties including R. chinensis, R.laevigata, R. tanguticum, N.nucifera, A. gracilistylus and B. cusia, was obtained.
    Advisor Committee
  • Shiow-Ling Lee - advisor
  • none - co-chair
  • none - co-chair
  • Files indicate in-campus access only
    Date of Defense 2004-07-29 Date of Submission 2004-09-27


    Browse | Search All Available ETDs